A Case of Severe Seronegative Inflammatory Arthritis due to Nivolumab and Review of the Literature
Identifieur interne : 000B50 ( Main/Exploration ); précédent : 000B49; suivant : 000B51A Case of Severe Seronegative Inflammatory Arthritis due to Nivolumab and Review of the Literature
Auteurs : Bicky Thapa [États-Unis] ; Asad Ali [États-Unis] ; Raunak Nair [États-Unis] ; Rishik Vashisht [États-Unis] ; Cassandra Calabrese [États-Unis]Source :
- Case Reports in Rheumatology [ 2090-6889 ] ; 2019.
Abstract
Immune-checkpoint inhibitors (ICIs) have revolutionized the treatment of cancer, yet therapy is often hampered by immune-related adverse events (irAEs) which range from mild to severe life-threatening events. Musculoskeletal (MSK) irAEs leading to discontinuation of ICIs are uncommon but increasingly recognized. We report a challenging case of severe immune-related seronegative inflammatory arthritis due to nivolumab in a patient with stage IV metastatic adenocarcinoma.
Url:
DOI: 10.1155/2019/1326734
PubMed: 31781462
PubMed Central: 6875374
Affiliations:
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Musculoskeletal (MSK) irAEs leading to discontinuation of ICIs are uncommon but increasingly recognized. We report a challenging case of severe immune-related seronegative inflammatory arthritis due to nivolumab in a patient with stage IV metastatic adenocarcinoma.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Dine, J" uniqKey="Dine J">J. Dine</name></author><author><name sortKey="Gordon, R" uniqKey="Gordon R">R. Gordon</name></author><author><name sortKey="Shames, Y" uniqKey="Shames Y">Y. Shames</name></author><author><name sortKey="Kasler, M" uniqKey="Kasler M">M. Kasler</name></author><author><name sortKey="Barton Burke, M" uniqKey="Barton Burke M">M. Barton-Burke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Sharma, P" uniqKey="Sharma P">P. Sharma</name></author><author><name sortKey="Allison, J P" uniqKey="Allison J">J. P. 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